What is Conolidine? Very simply put, it is an alkaloid. Unfortunately, a more complicated answer is warranted for this question. So, please bear with our science jargon as much as possible, and try to enjoy the ride! Let’s define the term alkaloid first.
An alkaloid is defined as any of a class of organic compounds of plant origin which have strong physical effects on humans and contain Nitrogen. They include many drugs (morphine, quinine) and poisons (atropine, strychnine). Conolidine is derived from the Crepe Jasmine plant, and it can have a pronounced effect on pain transmission in the brain.
The real question, now that we’ve defined Conolidine as an alkaloid, is what does Conolidine do and why take it?
Conolidine is one of 66 naturally occurring alkaloids found within the bark and whole plant of Crepe Jasmine. Recently, studies have been conducted to determine if Conolidine has any efficacy on the human body.
What was discovered is nothing short of miraculous. The Conolidine alkaloid can have analgesic effects while not interacting with traditional pain receptors. Opiates, on the other hand, cannot share that same claim.
Conolidine can treat pain, what does that have to do with me?
What this means is that we can effectively treat pain in the same manner as traditional opiates. However, now we can stay away from the negative side effects. More than that, this compound works on what’s referred to as scavenging opioid receptors that regulate opioid peptides naturally in the body.
Your body is extremely sophisticated chemically. When the brain reads a transmission of a pain signal, your body automatically goes to work producing and delivering painkillers.
This scavenger receptor is what regulates the amount of painkillers that your brain receives. This is what allow Conolidine to kill the pain signals. Conolidine will interact with this receptor and allow your body’s natural system to do its job and alleviate the pain with natural production.
Additionally, Conolidine will interact with the scavenger opioid receptor to alleviate pain much as a traditional opiate does, but will not initiate the same chain of reactions that lead to addiction.
So, what’s the bottom line?
Conolidine is an alkaloid found within the bark of the Crepe Jasmine plant. It has been used for centuries in traditional Chinese and Ayurvedic medicine, and has been found to assist in the alleviation of pain.
It is safe to say the community at large can start to have hope for a safer painkiller. One that doesn’t carry with it the baggage of addiction and overstimulation of brain chemistry. It is out hope that these benefits will ultimately lead to a safer and more effective way to treat pain.

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