The Conolidine alkaloid found in the Crepe Jasmine or Tabernaemontana divaricata plant is fast becoming a point of interest for those seeking alternative treatments for pain. However, if it can treat pain, then does Conolidine have the same side effects? Is Conolidine Addictive?
With early studies showing that Conolidine may be as potent in relieving pain as leading opiate based painkillers, it is natural to wonder whether or not the same issues might arise with this “new” alkaloid. We know all too well what happens when an addictive and easy to get painkiller runs rampant.
Traditionally, though effective, opiate and opioid painkillers have extreme drawbacks. From addiction all the way to side effects as severe as death, and people want to know if Conolidine comes with the same risks. The last thing you want to find out is that you have access to a natural and safe painkiller only to then find out it has caveats.
Unlike opiate based painkillers, Conolidine is not itself an opiate. Conolidine has been studied to show that it works by activating “scavenger” receptors in the brain. These receptors are ones that help to alleviate pain.

So, Is Conolidine Addictive?
This revelation is comforting as opiates work on opioid receptors in the brain that can set off a chain reaction. This chain reaction spews tons of pleasure chemicals like dopamine and oxytocin.
Luckily, with Conolidine this is not the issue. Conolidine alleviates pain without triggering potentially deadly addictive chemicals and therefore behavior.
People are becoming more conscious of Conolidine as an option for pain relief. It is a comfort to know that options exist that do not carry the same baggage as more traditional methods.
For now, we think it’s extremely safe to say that Conolidine is NOT addictive. In fact, based on the science, it would appear that Conolidine has none of the traditional hallmarks of an addictive substance whatsoever.
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