People tout Conolidine as nature’s Morphine in some circles, so let’s go over its history and see what Conolidine products companies have been offering.
Conolidine has been around for a very long time as a supplement for treating many conditions. Though, it has never really been an ingredient used a lot in Dietary Supplements.
Crepe Jasmine (Tabernaemontana divaricata) has a history of use that goes back millennia. People use it in traditional Chinese and Ayurvedic medicine now and have so for a long time. Some companies are even working tirelessly to provide a Conolidine drug. So, let’s see what Dietary Supplements are springing up while that goes on.
It should come as no surprise that only potential pain relief offerings are found in a quick search. All of the products we are finding are “full-spectrum” extractions of the Crepe Jasmine plant. After all, many studies are ongoing regarding Conolidine’s effects as a pain reliever.
Conolidine 1: The Original “Nature’s Morphine”

Pharm Origins is a brand you will see many in this article. Our deep dive on Conolidine products only led to this brand so that this article may seem like a history on Pharm Origins. With that said, the photo above is one of their first offerings cerca 2016.
This product, Conolidine 1™, seems to be a solvent-based tincture of the entire plant standardized to 750mg per dose. The company uses Crepe Jasmine (Tabernaemontana divaricata) in powder form. Then, they extract all of the alkaloids from the material using alcohol of some kind. This is known as a full-spectrum extraction.
This type of extraction is the best-case scenario for those looking for alternative treatments. This is important if you want a product as natural as possible. This particular product does not even boast flavoring as an additive, and I imagine that’s why we have our next entry.
Conolidine Could Use Some Flavor Historically…

At first, this offering of Conolidine 1™ may appear no different than the previous one listed aside from two marked differences; strength of dose and flavor.
We imagine that a fly on the wall at Pharm Origins would know that an alcohol-based, non-flavored extraction of Crepe Jasmine would taste… undesirable.
As with most things in supplemental health, that which tastes the worst does the best work. So, knowing that, we certainly applaud Pharm Origins for going the all-natural route, but we’re happy to see a flavored option.
Conolidine 1’s Final Iteration in History?

As much as the next person, we like orange flavor, but here is the most recent version of Pharm Origin’s Conolidine 1™, flavored with strawberry instead.
Sporting the same upgrade in strength and a clinical version that has twice as much Crepe Jasmine, this version of Conolidine 1™ seems to be the apex. Introduced circa 2019, this is the most recent version we can find on the internet right now.
Frankly, we are very impressed with these Conolidine products from a purely impartial perspective. Full-spectrum extractions of Crepe Jasmine are the safest products to go with for Conolidine supplementation if possible.
The only thing we are missing from the product list has been synthesized in a laboratory, but that landmark seems not to be too far out based on clinical studies.
In addition, when reviewing the history of Conolidine and its products, we ran across an innovation from another company we follow on this blog.
Winters Biotechnology recently announced a new Conolidine ingredient called CONOCB2™ in a press release you can read here.
Could you explain just what it can benefit from this product? Your Truly Cleah Williams