There are a ton of questions regarding Conolidine, but a common one we get is “Can Conolidine be Synthesized?”. We started this blog in the first place to keep you all as informed as possible. To that purpose, today, we will be answering a common question we hear. Can Conoldine be Synthesized?
You may be asking yourself what “synthesize” means, and you’re not alone. Synthesis is defined as “Chemistry. the forming or building a more complex substance or compound from elements or simpler compounds.”
Simply put, synthesizing a compound allows one to create high concentrations of compounds. This is particularly useful when a combination like Conolidine occurs naturally in only small amounts.
We always tell you that when any information regarding Conoidine is available to us, we want you to have it. In that interest, we have excellent info to share with you.
This is not new information, but it is worth revisiting. In 2011, a study outlined a chemical means to synthesize Conolidine in large amounts. Suffice it to say that this is extremely important and positive news.

So, Can Conolidine Be Synthesized Now?
This fantastic news from Scripps Research Institute is nothing short of miraculous. Now that Conolidine CAN be synthesized (link to original article), what does this mean for the compound?
Conolidine being synthesized changes the playing field for end-use products exponentially. Essentially, this discovery allows for larger doses of Conolidine to be given to mice for models.
These mice models are then compared to human testing, and (hopefully) human trials can begin on Conolidine in a closed study. These types of trials will give us the definitive answer on Conolidine when it’s all said and done.
Knowing that Conolidine can be synthesized means that whole-plant extractions of Crepe Jasmine (Tabernaemontana divaricata) will not be the only way to get Conolidine. This also means that the likelihood of a formal drug being made by a Big Pharma company is very high because the compound can be changed.
This means that they can apply copyright to that compound as well.
Overall, this is an excellent development. Companies will prioritize Conolidine regarding R&D. More research means more end-use products, which is a big win for everyone looking for alternative pain treatments.
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