How Does Conolidine Work?

One of the more complicated questions we receive is how does Conolidine work? Conolidine is an alkaloid found in the Crepe Jasmine (Tabernaemontana divaricata) plant. At Conolidine.com we try to inform you with the most up to date Conolidine information possible. We feel like a general understanding of how Conolidine works is a must for an enthusiast.

A newly identified opioid pain receptor, ACKR3/CXCR7, which regulates opioid peptides in the brain, has been found to have an affinity for the Conolidine alkaloid. As a result, this peptide is activated, and it allows for your body’s naturally produced opioids to bind to the four common receptors in the brain, which then assists in natural analgesic effects moreover.

Not only does the Conolidine alkaloid show in studies its own potential and incredible analgesic effects, but on a neurochemical level, it shows that it can naturally allow your body to treat pain more effectively.

Simply put, the Conolidine alkaloid comes from a perennial shrub that is extremely common to many regions of the globe.

If properly used, qualified, and verified, it seems the Tabernaemontana divaricata plant shows extreme promise in regard to safe, non-addictive, and effective pain relief.

So, How Does Conolidine Work?

Conolidine works on the central nervous system. It works on the “CPU” of the central nervous system (CNS), the brain. Much like traditional medicinal pain treatment options, the main compound attaches to a receptor.

From here, Conolidine works like an opioid. By contacting the receptor, Conolidine initiates a chemical reactions that has been shown to alleviate pain in mouse models. One can assume from this data that the same will be seen to some degree in human trials as well.

We hope this article sheds some light on the science behind Conolidine. Too often, companies offer a lengthy, jumbled explanation of their products. As we navigate the world of Conolidine, we will do our absolute best to keep you informed of any news. In the meantime, this should offer a small window into the question: How Does Conolidine Work?